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| Direction | Distance |
| 1: Start out going South on FORT MYER DR towards KEY BLVD by turning right. | 0.2 miles (0.3 km) |
| 2: Turn LEFT onto WILSON BLVD. | 0.2 miles (0.4 km) |
| 3: Take the VA-110 SOUTH ramp. | 0.1 miles (0.2 km) |
| 4: Merge onto JEFFERSON DAVIS HWY. | 1.0 miles (1.7 km) |
| 5: Take the WASHINGTON BLVD ramp towards COLUMBIA PIKE(I-395 S). | 0.3 miles (0.5 km) |
| 6: Merge onto WASHINGTON BLVD. | 0.7 miles (1.2 km) |
| 7: Take the I-395 SOUTH ramp towards RIDGE RD/RICHMOND. | 0.3 miles (0.5 km) |
| 8: Merge onto I-395 S. | 8.1 miles (13.1 km) |
| 9: I-395 S becomes I-95 S. | 118.4 miles (190.4 km) |
| 10: Take the I-85 SOUTH exit, exit number 51, towards DURHAM(US-460 W)/ATLANTA. | 0.5 miles (0.8 km) |
| 11: Merge onto I-85 S. | 128.2 miles (206.3 km) |
| 12: Take US-15 BYP S. | 4.0 miles (6.4 km) |
| 13: Take the US-15 SOUTH/US-501 SOUTH exit, exit number 105A, towards CHAPEL HILL(I-40). | 0.3 miles (0.5 km) |
| 14: Merge onto DURHAM CHAPEL HILL BLVD. | 3.5 miles (5.6 km) |
| 15: DURHAM CHAPEL HILL BLVD becomes US-15 S. | 2.3 miles (3.8 km) |
| 16: Take the ramp towards UNC CHAPEL HILL. | 0.1 miles (0.2 km) |
| 17: Turn RIGHT onto RALEIGH RD. | 0.8 miles (1.3 km) |
| 18: RALEIGH RD becomes SOUTH RD. | 0.7 miles (1.1 km) |
| 19: Turn SLIGHT RIGHT onto S COLUMBIA ST. | 0.2 miles (0.4 km) |
| 20: Turn LEFT onto FRATERNITY CT. | 0.0 miles (0.0 km) |
| Total Distance: | 270.1 miles (434.6 km) |
| Estimated Time: | 5 hours, 6 minutes |